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RStudio r software v.4.3.1
R Software V.4.3.1, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/r software v.4.3.1/product/RStudio
Average 90 stars, based on 1 article reviews
r software v.4.3.1 - by Bioz Stars, 2026-06
90/100 stars

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Early synaptosomal-Associated protein 25 (SNAP-25) long-term prognosis on severe traumatic brain injury (TBI). ( A ) Strong trend towards higher levels of SNAP-25 at D2–D3 and D5–D6 in patients with unfavourable versus favourable outcome (Glasgow Outcome Scale Extended (GOSE) at 6 months 1–3 vs 4–8). ( B ) Comparison of visinin-like protein 1 (VILIP-1) values between favourable (4–8) or unfavourable (1–3) GOSE. ( C–F ) <t>Principal</t> <t>component</t> analysis <t>(PCA)</t> ( C,E ) and PCA vector ( D–F ) analysis for the favourable versus non-favourable outcome groups. The first two dimensions explain approximately 74% ( C ) to 78% ( E ) of variance. SNAP-25 and VILIP-1 vectors diverge from the other neuroaxonal and glial damage markers at D1 ( D ) but not at D5 ( F ). Each data point represents one patients/timepoint; median and IQR are depicted (black bars). Group size and significance are reported in the graphs. *P<0.05.
R Studio Software V.4.3.1, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/r-studio software v.4.3.1/product/RStudio
Average 90 stars, based on 1 article reviews
r-studio software v.4.3.1 - by Bioz Stars, 2026-06
90/100 stars
  Buy from Supplier

90
RStudio r studio software v. 4.3.1
Early synaptosomal-Associated protein 25 (SNAP-25) long-term prognosis on severe traumatic brain injury (TBI). ( A ) Strong trend towards higher levels of SNAP-25 at D2–D3 and D5–D6 in patients with unfavourable versus favourable outcome (Glasgow Outcome Scale Extended (GOSE) at 6 months 1–3 vs 4–8). ( B ) Comparison of visinin-like protein 1 (VILIP-1) values between favourable (4–8) or unfavourable (1–3) GOSE. ( C–F ) <t>Principal</t> <t>component</t> analysis <t>(PCA)</t> ( C,E ) and PCA vector ( D–F ) analysis for the favourable versus non-favourable outcome groups. The first two dimensions explain approximately 74% ( C ) to 78% ( E ) of variance. SNAP-25 and VILIP-1 vectors diverge from the other neuroaxonal and glial damage markers at D1 ( D ) but not at D5 ( F ). Each data point represents one patients/timepoint; median and IQR are depicted (black bars). Group size and significance are reported in the graphs. *P<0.05.
R Studio Software V. 4.3.1, supplied by RStudio, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/r studio software v. 4.3.1/product/RStudio
Average 90 stars, based on 1 article reviews
r studio software v. 4.3.1 - by Bioz Stars, 2026-06
90/100 stars
  Buy from Supplier

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Early synaptosomal-Associated protein 25 (SNAP-25) long-term prognosis on severe traumatic brain injury (TBI). ( A ) Strong trend towards higher levels of SNAP-25 at D2–D3 and D5–D6 in patients with unfavourable versus favourable outcome (Glasgow Outcome Scale Extended (GOSE) at 6 months 1–3 vs 4–8). ( B ) Comparison of visinin-like protein 1 (VILIP-1) values between favourable (4–8) or unfavourable (1–3) GOSE. ( C–F ) Principal component analysis (PCA) ( C,E ) and PCA vector ( D–F ) analysis for the favourable versus non-favourable outcome groups. The first two dimensions explain approximately 74% ( C ) to 78% ( E ) of variance. SNAP-25 and VILIP-1 vectors diverge from the other neuroaxonal and glial damage markers at D1 ( D ) but not at D5 ( F ). Each data point represents one patients/timepoint; median and IQR are depicted (black bars). Group size and significance are reported in the graphs. *P<0.05.

Journal: Journal of Neurology, Neurosurgery, and Psychiatry

Article Title: Dynamics of synaptic damage in severe traumatic brain injury revealed by cerebrospinal fluid SNAP-25 and VILIP-1

doi: 10.1136/jnnp-2024-333413

Figure Lengend Snippet: Early synaptosomal-Associated protein 25 (SNAP-25) long-term prognosis on severe traumatic brain injury (TBI). ( A ) Strong trend towards higher levels of SNAP-25 at D2–D3 and D5–D6 in patients with unfavourable versus favourable outcome (Glasgow Outcome Scale Extended (GOSE) at 6 months 1–3 vs 4–8). ( B ) Comparison of visinin-like protein 1 (VILIP-1) values between favourable (4–8) or unfavourable (1–3) GOSE. ( C–F ) Principal component analysis (PCA) ( C,E ) and PCA vector ( D–F ) analysis for the favourable versus non-favourable outcome groups. The first two dimensions explain approximately 74% ( C ) to 78% ( E ) of variance. SNAP-25 and VILIP-1 vectors diverge from the other neuroaxonal and glial damage markers at D1 ( D ) but not at D5 ( F ). Each data point represents one patients/timepoint; median and IQR are depicted (black bars). Group size and significance are reported in the graphs. *P<0.05.

Article Snippet: The principal component analysis (PCA) was performed using R-studio software (V.4.3.1).

Techniques: Comparison, Plasmid Preparation